Septal flattening (D-sign)

Septal flattening, often referred to as the “D-sign” in cardiac ultrasound, is a crucial indicator of right ventricular pressure overload. This phenomenon occurs when the interventricular septum, typically curved towards the right ventricle, flattens or shifts towards the left ventricle due to increased pressure within the right heart chambers. It’s a key diagnostic sign in conditions like pulmonary hypertension or right ventricular infarction.

Recognizing the D-sign on echocardiography is vital for rapid assessment of right heart hemodynamics. Ultrasound imaging clearly visualizes this change in septal configuration, providing immediate insights into cardiac function and guiding clinical management. This visual cue helps differentiate various cardiac pathologies and aids in determining the severity of right ventricular dysfunction.

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